Axon Axoclamp 900A Microelectrode Amplifier A computer-controlled amplifier for current-clamp and voltage- clamp applications

The Axon™ Axoclamp™ 900A Amplifier is the latest microelectrode amplifier from Molecular Devices®. Like the Axoclamp 2B amplifier, the Axon Axoclamp

900A Amplifier offers several modes of operation that measure signals from single cells, tissue slices and whole animal preparations.  The advanced signal conditioning included in the Axon Axoclamp 900A Amplifier saves the expense of buying additional hardware and frees up valuable space in an electrophysiology setup.

By making  the amplifier computer-controlled, several powerful new features have been added

to make it simpler to set up and run experiments. This exciting new instrument is designed to meet researchers’ needs today, as well as offer flexibility for future experiments.

Axoclamp 900A

Axon Axoclamp Commander Software interface

The Axon Axoclamp 900A Amplifier is fully integrated with Axon Axoclamp Commander Software.  The figure to the left shows many of the features of the software interface, including the different modes available, controls for I-Clamp mode in Channel 1 and output signal conditioning controls. Although controlled by software, the Axon Axoclamp 900A Amplifier uses customary analog inputs and outputs instead of a built-in digitizer. Thus, the amplifier can be used with any external digitizer and acquisition software package, including Molecular Devices’ Axon Digidata® Digitizers and Axon pCLAMP® Data Acquisition and Analysis Software. Using

the Axoclamp 900A Amplifier with the Axon Digidata 1440A Digitizer and Axon pCLAMP 10

Software enables full telegraphing of the Axon Axoclamp 900A Amplifier parameters.

Conventional Interface with SoftPanel Controller

o offer a more conventional method of amplifier control,the optional SoftPController was designed as a hardware extension of the Axoclamp Commander Software. The SoftPcontroller communicates with the computer via an easy-to-set-up USB 2.0 connection. Using the SoftPanel Controller
does not negate the many benefits afforded by computer control of the
amplifier.

SoftPanel Controller

Headstage with baseplate

The small profile of the miniaturized HS-9A and VG-9A headstages makes it easy to incorporate them into an electrophysiology set up. The dovetail design
integrates with a baseplate for easy attachment to micromanipulators.

Headstage